Definition: An increase in pH, secondary to a loss of fluid volume.
Mechanism: Fluid loss leads to an activation of the RAAS system. And Angiotensin II activates the Na-H anti-porter in the distal tubule. So more Na+ is being absorbed while H+ is being lost. This helps retain fluid, at the expense of losing H+ ion. So as the body is trying to retain fluid, the pH rises.
Treatment: Simply to treat the underlying fluid loss. The pH should correct on its own
Source: http://en.wikipedia.org/wiki/Contraction_alkalosis
Another source that may be helpful: http://www.usmle-forums.com/usmle-step-1-forum/841-ii-contraction-alkalosis.html
Extra:
Apparently, this can have something to do with Hypo-chloremia. See slide 35 of bk9.wk2.AcidBaseLab
Tuesday, April 12, 2011
Monday, April 11, 2011
Aldosterone Mechanism
Sunday, April 10, 2011
EKG Leads and Heart Locations
Anterior - V2, V3, V4
Right ventricular - AVR, I
Left lateral - , I AVL, V5, V6
Inferior - AVF, II, III
Right ventricular - AVR, I
Left lateral - , I AVL, V5, V6
Inferior - AVF, II, III
Tuesday, April 5, 2011
Venous Return Curves
For now, I will just provide links to good reading. Note this is a confusing topic, and I still don't quite get it.
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